Research Articles

Xiaoyan Ren*, Renju Dou, Qin Wang, Kaixin Hu, Kaihua Sun, Chen Liu, Lehui Lu*, “A Biocompatible Deep Eutectic Electrolyte Enables Ultra-fast Charging in Lithium-ion Batteries” Adv. Funct. Mater., 2025, 2500464.

Chen Liu, Yuting Jiang, Xingda Mu, Xuling Chang, Ye Zhang, Xiaoxiao He*, Xiaojuan Zhu, Wenbo Sun*, Lehui Lu* “ Bionic Synapses for Real-time Epileptic Seizure Control” Sens. and Actuators B, 2025, 429, 137304.

Rupeng Liu, Chunhuan Jiang, Jinhan Guo, Yue Zheng, Leting Zhang, Xiaolong Liang, Huimin Gao, Jiancheng Zhao, Yunhang Fan, Qing Chen, Wenhui He*, Lehui Lu* “Activating Ru Nanoclusters for Robust Oxygen Reduction in Aqueous Wide-temperature Zinc-air Batteries” Matter, 2024, 7, 4031-4045.

Yang Li, Qianqian Zhang, Yuzhu Wang, Shiqing Li, Chunhuan Jiang, Lehui Lu* “Ultrasound-induced In Situ Dopamine Polymerization and Deep Mucosal Penetration for Intraluminal Drug Administration” ACS Nano, 2024, 18, 20611-20623. 

Yang Li, Qianqian Zhang, Zhen Sun, Mingjie Rong, Chunhuan Jiang, Lehui Lu* “Unexpected Emergence of Carbon-centered Radical from Piezoelectric Effect in Oleic Acid-capped BaTiO3” ACS Nano, 2024, 18, 9645-9655.

Yuzhu Wang, Yang Li, Chunhuan Jiang, Qianqian Zhang, Shiqing Li, Wenbo Sun, Tong Li, Lehui Lu* “Self-directed Assembly Drives Spatial Confinement Polymerization for Controlled Capsule Engineering” Nano Today, 2024, 57, 102405.

Jian Liu, Mingjie Rong, Wenbo Sun, Bin Yu*, Lehui Lu* “A New Strategy to Fight Tumor Heterogeneity: Integrating Metal-defect Active Centers within NADH Oxidase Nanozymes” Nano Today, 2024, 54, 102113.

Yulai Pu, Qin Wang, Renju Dou, Xiaoyan Ren*, Lehui Lu* “A Crown-ether-enabled Eutectic Electrolyte for Ultra-high Temperature Lithium Metal Batteries” Energy Storage Mater., 2024, 67, 103285.

Wenbo Sun, Bin Yu, Dianshuai Huang, Chunhuan Jiang, Wei Wang, Jianhua Liu, Zonghua Wang*, Lehui Lu* “Aggregation-induced T1/T2 Contrast Enhancement for Magnetic Resonance Imaging-guided Intraoperative Surgery” Sci. China Chem., 2024, 67, 2046–2055.

Mingjie Rong, Jian Liu, Lehui Lu*, “Self-assembly of 2D Polyphthalocyanine in Lysosome Enables Multi-enzyme Activity Enhancement to Induce Tumor Ferroptosis” Adv. Healthcare Mater., 2024, 2400325.

Mingjie Rong, Jian Liu, Zhen Sun, Tong Li, Yang Li, Chunhuan Jiang, Lehui Lu*, “Rational Utilization of Black Phosphorus Nanosheets to Enhance Palladium-Mediated Bioorthogonal Catalytic Activity for Activation of Therapeutics” Angew. Chem. Int. Ed., 2023, doi:10.1002/ange.202216822.

Xiaoyan Ren*, Qin Wang, Yulai Pu, Qi Sun, Wenbo Sun, Lehui Lu* “Synergizing Spatial Confinement and Dual-metal Catalysis to Boost Sulfur Kinetics in Lithium–sulfur Batteries” Adv. Mater., 2023, 35, 2304120.

Qin Wang, Qi, Sun, Yulai Pu, Wenbo Sun, Chengjiang Lin, Xiaozheng Duan*, Xiaoyan Ren*, Lehui Lu* “Light Mediated Li-ion Transport for Solid-state Lithium Batteries” Small, 2023, 19, 2309501.

Qi, Sun, Yang Li, Xiaoyan Ren, Jingwei Tao*, Lehui Lu*, “Revealing Performance Enhancement Mechanism for Lithium-sulfur Battery Using In-situ Electrochemical-fluorescence Technology” Small Methods, 2023, 7, 2300523.

Qianqian Zhang, Yang Li, Chunhuan Jiang, Wenbo Sun, Jingwei Tao*, Lehui Lu*, “Near-infrared Light-enhanced Generation of Hydroxyl Radical for Cancer Immunotherapy” Adv. Healthcare Mater., 2023, 12, 2301502.

Chen Liu, Jianan Xu, Yang Li, Chunhuan Jiang, Han Gao, Xiaoyan Ren, Lehui Lu* “The Microstructure-activity Relationship of Metal-organic Framework-based Electrocatalysts for Oxygen Evolution Reaction at the Single-particle Level” ACS Materials Lett., 2023, 5, 1902-1910.

Chen Liu, Jianan Xu, Han Gao, Min Zhou*, Lehui Lu* “Nitrogen-skinned Carbon Nanocone Enables Non-dynamic Electrochemistry of Individual Metal Particles” Sci. China Chem., 2022, 65, 2031-2037.

Qianqian Zhang, Zhen Sun, Wenbo Sun, Bin Yu, Chunhuan Jiang*, Lehui Lu*, “Engineering a Synergistic Antioxidant Inhibition Nanoplatform to Enhance Oxidative Damage in Tumor Treatment” Acta. Biomater., 2023, 158, 625-636.

Weihua Chen, Zhen Sun, Chunhuan Jiang, Wenbo Sun, Bin Yu, Wei Wang, Lehui Lu*, “An All-in-One Organic Semiconductor for Targeted Photoxidation Catalysis in Hypoxic Tumor” Angew. Chem. Int. Ed., 2021, 60, 16641-16648.

Bin Yu, Wei Wang, Wenbo Sun, Chunhuan Jiang, Lehui Lu*, “Defect Engineering Enables Synergistic Action of Enzyme-Mimicking Active Centers for High-Efficiency Tumor Therapy” J. Am. Chem. Soc., 2021, 143, 8855-8865.

Weihua Chen, Zhen Sun, Lehui Lu*, “Targeted Engineering of Medicinal Chemistry for Cancer Therapy: Recent Advances and Perspectives” Angew. Chem. Int. Ed., 2021, 60, 5626-5643.

Juan Wang, Daoqing Fan, Chunhuan Jiang, Lehui Lu*, “Host-Guest Interaction-mediated Nanointerface Engineering for Radioiodine Capture” Nano Today, 2021, 36, 101034.

Yang Li, Weihua Chen, Lehui Lu*, “Wearable and Biodegradable Sensors for Human Health Monitoring” ACS Appl. Bio Mater., 2021, 4, 122-139.

Zhen Sun, Weihua Chen, Wenbo Sun, Bin Yu, Qianqian Zhang, Lehui Lu*, “Nanoparticles: Untying the Gordian Knot in Conventional Computed Tomography Imaging” CCS Chemistry, 2021, 3, 1242-1257.

Zhen Sun, Weihua Chen, Jianhua Liu, Bin Yu, Chunhuan Jiang*, Lehui Lu*, “Mitochondria-Targeting Enhanced Phototherapy by Intrinsic Characteristics Engineered “One-for-All” Nanoparticles” ACS Appl. Mater. Interf., 2021, 13, 35568-35578.

Zelun Li, Juan Wang, Qian Chen, Kelong Ai*, Lehui Lu* “Hierarchically Porous Polymer with Ultra-high Affinity for Bisphenol A Enables High Efficient Water Purification” Sci. China Chem., 2021, 64, 1389-1400.

Wei Wang, Bin Yu, Wenbo Sun, Chunhuan Jiang*, Lehui Lu* “Bioinspired Nanostructured Spiderweb for High-efficiency Capturing and Killing of Bacteria” Sci. China Mater., 2021, 64, doi: 10.1007/s40843-021-1746-4.

Xiaoyan Ren, Qi Sun, Youliang Zhu, Wenbo Sun, Yang Li*, Lehui Lu*, “Unveiling the Role of Hydroxyl Architecture on Polysulfide Trapping for High-performance Lithium-sulfur Batteries” ACS Appl. Energy Mater., 2020, 3, https://doi.org/10.1021/acsaem.0c00444.

Wenya He, Xiaoyan Ren, Zhiqiang Yan*, Jin Wang*, Lehui Lu*, “Porous β-cyclodextrin Nanotubular Assemblies Enable High-efficiency Removal of Bisphenol Micropollutants from Aquatic Systems” Nano Res., 2020, 13, https://doi.org/10.1007/s12274-020-2758-0.

Bin Yu, Kelong Ai*, Lehui Lu*, “Dual-protective Nano-sunscreen Enables High-efficient Elimination of the Self-derived Hazards” Appl. Mater. Today, 2020, 18, 100493 (1-10).

Weihua Chen, Jianhua Liu, Ying Wang, Chunhuan Jiang, Bin Yu, Zhen Sun, Lehui Lu*, “A C5N2 Nanoparticle-based Direct Nucleus Delivery Platform for Synergistic Cancer Therapy” Angew. Chem. Int. Ed., 2019, 58, 6290-6294.

Hydrogen Bond-mediated Strong Adsorbent-I3− Interactions Enable High-efficiency Radioiodine Capture, Juan Wang, Zelun Li, Changting Wei, Ying Wang, Kelong Ai*, Lehui Lu*, Mater. Horiz., 2019, 6, 1517-1525.

Flame-Retardant Porous Hexagonal Boron Nitride for Safe and Effective Radioactive Iodine Capture, Juan Wang, Kelong Ai*, Lehui Lu*, J. Mater. Chem. A, 2019, 7, 16850-16858.

Xiaoyan Ren, Jiawei Wang, Zhangquan Peng*, Lehui Lu*, “Direct Monitoring of Trace Water in Li-ion Batteries Using Operando Fluorescence Spectroscopy” Chem. Sci., 2018, 9, 231-237.

Zelun Li, Xuling Chang, Ying Wang, Changting Wei, Juan Wang, Kelong Ai*, Ye Zhang*, Lehui Lu*, “A Point-and-shoot Strategy for Rapid Identification of Alcoholic Beverages” Anal. Chem., 2018, 90, 9838-9844.

Ying Wang, Hanwen Pei, Yan Jia, Jianhua Liu, Zelun Li, Kelong Ai*, Zhongyuan Lu, Lehui Lu*, “Synergistic Tailoring of Electrostatic and Hydrophobic Interactions for Rapid and Specific Recognition of Lysophosphatidic Acid, an Early-stage Ovarian Cancer Biomarker” J. Am. Chem. Soc., 2017, 139, 11616-11621.

Yanlan Liu, Kelong Ai, Xiaoyuan Ji, Diana Askhatova, Rose Du, Lehui Lu*, Jinjun Shi*, “Comprehensive Insights into the Multi-antioxidative Mechanisms of Melanin Nanoparticles and Their Application to Protect Brain from Injury in Ischemic Stroke” J. Am. Chem. Soc., 2017, 139, 856-862.

Yuanyuan Li, Shunjie Liu, Xun Zhao, Ying Wang, Jianhua Liu*, Xianhong Wang* , Lehui Lu*, “CO2-based Amphiphilic Polycarbonate Micelles Enable a Reliable and Efficient Platform for Tumor Imaging” Theranostics, 2017, 7, 4689-4698.

Wenya He, Kelong Ai, Xiaoyan Ren, Shengyan Wang, Lehui Lu*, “Inorganic Layered Ion-exchangers for Decontamination of Toxic Metal Ions in Aquatic Systems” J. Mater. Chem. A, 2017, 5, 19593-19606.

Changting Wei, Mengxia Shen, Kelong Ai, Lehui Lu*, “Transformation from FeS/Fe3C Nanoparticles Encased S, N Dual Doped Carbon Nanotubes to Nanosheets for Enhanced Oxygen Reduction Performance” Carbon, 2017, 123, 135-144.

Chunhuan Jiang, Ying Wang, Jiawei Wang, Wei Song*, Lehui Lu*, “Achieving Ultrasensitive in Vivo Detection of Bone Crack with Polydopamine-capsulated Surface-enhanced Raman Nanoparticle” Biomaterials, 2017, 114, 54-61.

Mengxia Shen, Changting Wei, Kelong Ai, Lehui Lu*, “Transition Metal-nitrogen-carbon Nanostructured Catalysts for Oxygen Reduction Reaction: From Mechanistic Insights to Structural Optimization” Nano Res., 2017, 10, 1449-1470.

Yuanyuan Li, Chunhuan Jiang, Dawei Zhang, Ying Wang, Xiaoyan Ren*, Kelong Ai, Xuesi Chen*, Lehui Lu*, “Targeted Polydopamine Nanoparticles Enable Photoacoustic Imaging Guided Chemo-photothermal Synergistic Therapy of Tumor” Acta. Biomater., 2017, 47, 124-134.

Kelong Ai, Changping Ruan, Mengxia Shen, Lehui Lu*, “MoS2 Nanosheets with Widened Interlayer Spacing for High-efficiency Removal of Mercury in Aquatic Systems” Adv. Funct. Mater., 2016, 26, 5542-5549.

Ying Wang, Chunhuan Jiang, Wenhui He, Kelong Ai, Xiaoyan Ren, Lin Liu, Mengchao Zhang*, Lehui Lu*, “Targeted Imaging of Damaged Bone in Vivo with Gemstone Spectral Computed Tomography” ACS Nano, 2016, 10, 4164-4172.

Wenhui He, Ying Wang, Chunhuan Jiang, Lehui Lu*, “Structure Effects of Carbon Matrix in Non-precious Metal O2-reduction Electrocatalysts” Chem. Soc. Rev., 2016, 45, 2396-2409.

Yan Chen, Kelong Ai, Jianhua Liu, Xiaoyan Ren, Chunhuan Jiang, Lehui Lu*, “Polydopamine-based Coordination Nanocomplex for T1/T2 Dual Mode Magnetic Resonance Imaging-guided Chemo-photothermal Synergistic Therapy” Biomaterials, 2016, 77, 198-206.

Mengxia Shen, Lirong Zheng, Wenhui He, Changping Ruan, Chuanhuan Jiang, Kelong Ai*, Lehui Lu* “High-performance Oxygen Reduction Electrocatalysts Derived from Uniform Cobalt-adenine Assemblies” Nano Energy, 2015, 17,120-130.

Yan Chen, Kelong Ai, Jianhua Liu, Guoying Sun, Qi Yin, Lehui Lu*, “Multifunctional Envelope-type Mesoporous Silica Nanoparticles for pH-responsive Drug Delivery and Magnetic Resonance Imaging” Biomaterials, 2015, 60, 111-120.

Mengxia Shen, Changping Ruan, Yan Chen, Chuanhuan Jiang, Kelong Ai*, Lehui Lu* “Covalently Entrapping of Cobalt-Iron Sulfides in N-doped Mesoporous Carbon as Extraordinary Bi-functional Electrocatalysts for Oxygen Reduction and Evolution Reactions” ACS Appl. Mater. Interf., 2015, 7, 1207-1218.

Wenhui He, Chunhuan Jiang, Jiabo Wang, Lehui Lu* “High-rate Oxygen Electroreduction over Graphitic-N Species Exposed on 3D Hierarchically Porous Nitrogen-doped Carbons” Angew. Chem. Int. Ed., 2014, 53, 9503-9507.

Changping Ruan, Kelong Ai, Xingbo Li, Lehui Lu* “A Superhydrophobic Sponge with Excellent Absorbency and Flame Retardancy” Angew. Chem. Int. Ed., 2014, 53, 5556-5560.

Yanlan Liu, Kelong Ai, Lehui Lu* “Polydopamine and Its Derivative Materials: Synthesis and Promising Applications in Energy, Environmental and Biomedical Fields” Chem. Rev., 2014, 114, 5057-5115.

Chenghua Zong, Li Rong Zheng, Wenhui He, Xiaoyan Ren, Chunhuan Jiang, Lehui Lu*, “In-situ Formation of Phosphorescent Molecular Gold (I) Cluster in a Macroporous Polymer Film to Achieve Colorimetric Cyanide Sensing” Anal. Chem., 2014, 86, 1687-1692.

Yan Chen, Kelong Ai, Yanlan Liu, Lehui Lu*, “A Tailor-made Charge-conversional Nanocomposite for pH-responsive Drug Delivery and Cell Imaging” ACS Appl. Mater. Interf., 2014, 6, 655-663.

Hongmei Sun, Wenhui He, Chenghua Zong, Lehui Lu*, “Template-free Synthesis of Renewable Macroporous Carbon via Yeast Cells for High-performance Supercapacitor Electrode Materials” ACS Appl. Mater. Interf., 2013, 5, 2261–2268.

Yanlan Liu, Kelong Ai, Jianhua Liu, Mo Deng, Yangyang He, Lehui Lu*, “Dopamine-melanin Colloidal Nanosphere: an Efficient Near-infrared Photothermal Therapeutic Agent for in Vivo Cancer Therapy” Adv. Mater., 2013, 25,1353-1359.

Kelong Ai, Yanlan Liu, Changping Ruan, Lehui Lu*, Gaoqing Max Lu*, “Sp2 C-dominant N-doped Carbon Submicrometer Spheres with Tunable Size: A Versatile Platform for Highly Efficient Oxygen Reduction Catalysts” Adv. Mater., 2013, 25, 998-1003.

Xiaojuan Liu, Chenghua Zong, Kelong Ai, Wenhui He, Lehui Lu*, “Engineering Natural Materials as Surface-enhanced Raman Spectroscopy Substrates for in Situ Molecular Sensing” ACS Appl. Mater. Interf., 2012, 4, 6599-6608.

Yanlan Liu, Kelong Ai, Lehui Lu* “Nanoparticulate X-ray Computed Tomography Contrast Agents: From Design Validation to in Vivo Applications” Acc. Chem. Res., 2012, 45, 1817-1827.

Chenghua Zong, Xiaojuan Liu, Hongmei Sun, Guo Zhang, Lehui Lu*, “New-type Nanoscale Coordination Particles：Toward Modification Free Detection of Hydrogen Sulfide Gas” J. Mater. Chem., 2012, 22, 18418-18425.

Yanlan Liu, Kelong Ai, Jianhua Liu, Qinghai Yuan, Yangyang He, Lehui Lu*, “Hybrid BaYbF5 Nanoparticles: Novel Binary Contrast Agent for High-resolution in Vivo X-ray Computed Tomography Angiography” Adv. Healthcare Mater., 2012, 1, 461-466.

Wenhui He, Lehui Lu*, “Revisiting the Structure of Graphene Oxide for Preparing New-style Graphene-based Ultraviolet Absorbers” Adv. Funct. Mater., 2012, 22, 2542-2549

Hongmei Sun, Lingyuan Cao, Lehui Lu*, “Bacteria Promoted Hierarchical Carbon Materials for High-performance Supercapacitor” Energy Environ. Sci., 2012, 5, 6206-6213.

Yanlan Liu, Kelong Ai, Jianhua Liu, Qinghai Yuan, Yangyang He, Lehui Lu*, “A High-performance Ytterbium-based Nanoparticulate Contrast Agent for in Vivo X-ray Computed Tomography Imaging” Angew. Chem. Int. Ed., 2012, 51, 1437-1442.

Wei Song, Zhu Mao, Xiaojuan Liu, Yong Lu, Zhishi Li, Bing Zhao*, Lehui Lu*, “Detection of Protein Deposition within Latent Fingerprints by Surface-enhanced Raman Spectroscopy Imaging” Nanoscale, 2012, 4, 2333-2338.

Chenghua Zong, Kelong Ai, Guo Zhang, Hongwei Li, Lehui Lu*, “Dual-emission Fluorescent Silica Nanoparticle-based Probe for Rapid and Ultrasensitive Detection of Cu2+” Anal. Chem., 2011, 83, 3126-3132.

Kelong Ai, Yanlan Liu, Jianhua Liu, Qinghai Yuan, Yangyang He, Lehui Lu*, “Large-scale Synthesis of Bi2S3 Nanodots as a Contrast Agent for in Vivo X-ray Computed Tomography Imaging” Adv. Mater., 2011, 23, 4886-4891.

Yanlan Liu, Kelong Ai, Qinghai Yuan, Lehui Lu*, “Fluorescence-enhanced Gadolinium-doped Zinc Oxide Quantum Dots for Magnetic Resonance and Fluorescence Imaging” Biomaterials, 2011, 32, 1185-1192.

Yanlan Liu, Kelong Ai, Lehui Lu*, “Designing Lanthanide-doped Nanocrystals with Both Up- and Down-conversion Luminescence for Anti-counterfeiting” Nanoscale, 2011, 3, 4804-4810.

Guo Zhang, Yanlan Liu, Qinghai Yuan*, Chenghua Zong, Jianhua Liu, Lehui Lu*, “Dual Modal in vivo Imaging Using Upconversion Luminescence and Enhanced Computed Tomography Properties” Nanoscale, 2011, 3, 4365-4371.

Hongmei Sun, Linyuan Cao, Lehui Lu*, “Magnetite/Reduced Graphene Oxide Nanocomposites: One Step Solvothermal Synthesis and Use as a Novel Platform for Removal of Dye Pollutants” Nano Res., 2011, 4, 550-562.

Hongmei Sun, Qinghai Yuan*, Baohua Zhang, Kelong Ai, Pengguo Zhang, Lehui Lu*, “GdⅢ Functionalized Gold Nanorods for Multimodal Imaging Applications” Nanoscale, 2011, 3, 1990-1996.

Kelong Ai, Y.anlan Liu, Lehui Lu*, Xiaoli Cheng, Lihua Huo “A Novel Strategy for Making Soluble Graphene Sheets Cheaply by Adopting Endogenous Reducing Agent” J. Mater. Chem., 2011, 21, 3365-3370.

Xiaojuan Liu, Linyuan Cao, Wei Song, Kelong Ai, Lehui Lu*, “Functionalizing Metal Nanostructured Film with Graphene Oxide for Ultrasensitive Detection of Aromatic Molecules by Surface-enhanced Raman Spectroscopy” ACS Appl. Mater. Interf., 2011, 3, 2944-2952.

Yanlan Liu, Kelong Ai, Xiaoli Cheng, Lihua Huo, Lehui Lu*, “Gold Nanocluster-based Fluorescent Sensor for Highly Sensitive and Selective Detection of Cyanide in Water” Adv. Funct. Mater., 2010, 20, 951-956.

Guo Zhang, Jianghua Feng*, Lehui Lu*, Baohua Zhang, Linyuan Cao “Fluorescent Magnetic Nanoprobes: Design and Application for Cell Imaging” J. Colloid Interf. Sci, 2010, 351, 128-133.

Lingyuan Cao, Yanlan Liu, Baohua Zhang, Lehui Lu*, “In Situ Controllable Growth of Prussian Blue Nanocubes on Reduced Graphene Oxide: Facile Synthesis and Their Application as Enhanced Nanoelectrocatalyst for H2O2 Reduction” ACS Appl. Mater. Interf., 2010, 8, 2339-2346.

Kelong Ai, Yanlan Liu, Lehui Lu*, “Hydrogen-bonding Recognition-induced Color Change of Gold Nanoparticles for Visual Detection of Melamine in Raw Milk and Infant Formula” J. Am. Chem. Soc., 2009, 131, 9496-9497

Kelong Ai, Baohua Zhang, Lehui Lu*, “Europium-based Fluorescence Nanoparticle Sensor for Rapid and Ultrasensitive Detection of an Anthrax Biomarker” Angew. Chem. Int. Ed., 2009, 48, 304-308.

Xinmei Zhao, Haishui Wang*, Baohua Zhang, Kelong Ai, Guo Zhang, Linyuan Cao, Xiaojuan Liu, Hongmei Sun, Lehui Lu*, “Monitoring Catalytic Degradation of Dye Molecules on the Silver-coated ZnO Nanowire Arrays by Surface-enhanced Raman Spectroscopy” J. Mater. Chem., 2009, 19, 5547-5553.

Baohua Zhang, Haishui Wang, Lehui Lu*, Kelong Ai, Guo Zhang, Xiaoli Cheng “Large-Area Silver-Coated Silicon Nanowire Arrays for Molecular Sensing Using Surface-enhanced Raman Spectroscopy” Adv. Funct. Mater., 2008, 18, 2348-2355.

Lehui Lu, Alexander Eychmüller* “Ordered Macroporous Bimetallic Nanostructures: Design, Characterization and Applications” Acc. Chem. Res., 2008, 41, 244-253.